2017년 2월 25일 토요일

Clonidine

Clonidine

Clonidine
Clonidine Structural Formulae V.1.svg
Material name by the IUPAC glossology
Clinical data
Fetus degree of risk classification
  • US: C
Legal regulation
  • JP: Prescription pharmaceutical products
  • Prescription (US) required
Dosage method Pass through oral; skin
Pharmacokinetics data
Bioavailability 75-95%
Plasma protein combination 20-40%
Metabolism Liver
Half-life 12-33 hours
Excretion Kidney (40-50%)
Identification
CAS number
(MeSH)
4205-90-7
ATC cord C02AC01 (WHO) N02CX02 (WHO), S01EA04 (WHO)
PubChem CID: 2803
DrugBank APRD00174
KEGG D00281
Chemical data
Chemical formula C9H9Cl2N3
Molecular weight 230.093 g/mol

The drug that clonidine (British: Clonidine) is used for treatment of the high blood pressure. I belong to selective α 2 receptor agonist pharmacologically. The brand name "Catapres" (Boehringer Ingelheim production sale)

I control the excitement of the preganglionic fiber by acting on α 2 receptor which is the subtype of the adrenergic receptor selectively and reduce blood pressure by controlling secretion of the noradrenaline.

Action is strong, and there is long α receptor blockade at action time and is less used for treatment itself of the high blood pressure too much now. I may be used as a load drug in the load examination of the phaeochromocytoma traditionally.

Table of contents

Effect, effect

Various high blood pressure [1]

Allied item

Source

Outside link

Catapres Tablets attachment document

This article is taken from the Japanese Wikipedia Clonidine

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