Secosteroid

Cholecalciferol which is an example of the 9,10-secosteroid

A steroid frame. The bond between C9 and the C10 of the B ring of the steroid is cut and becomes vitamin D.

Secosteroid (Secosteroid) is a steroid having a "broken" loop. With secare meaning "cutting" in Latin as for the word secosteroid [¹]^{: stere[1]: which means "a solid, three dimensions" in 241, Latin It comes from 129}. The secosteroid is done with the derivative of [²], the steroid with the classification of the steroid [³].

The subclassification of the secosteroid is decided by the position of the carbon atom of the steroid frame becoming the cause that the cutting of the ring occurs. For example, as for the 9,10-secosteroid, between a carbon atom of the ninth place and the tenth place of the B ring of the steroid is cut. To typical secosteroid with cholecalciferol and vitamin D3 [⁴].

Source

1. ^ ^{a b} Ayers D (1972). Bioscientific Terminology. Tucson: University of Arizona Press. ISBN 978-0-8165-0305-6. http://books.google.ca/books?id=CTwh-QaifQkC August 12, 2014 reading. . 
2. ^ Moss GP and the Working Party of the IUPAC-IUB Joint Commission on Biochemical Nomenclature. "The Nomenclature of Steroids". Queen Mary University of London. p. Section 3S-1 (esp. 3S-1.4, incl. note 4). August 12, 2014 reading. ; Moss GP (1989). "Nomenclature of Steroids" (Recommendations 1989). Pure & Appl. Chem. 61 (10): 1786f. doi: 10.1351/pac198961101783. http://www.chem.qmul.ac.uk/iupac/steroid/ August 12, 2014 reading. "Steroids are compounds possessing the skeleton of cyclopenta[a]phenanthrene or a skeleton derived therefrom by one or more bond scissions or ring expansions or contractions.", Hill RA, Makin HL, Kirk DN, Murphy GM (1991). Dictionary of Steroids (1st ed.). London: Chapman & Hall. ISBN 978-0-412-27060-4. 
3. ^ "Definition of secosteroid". Farlex Partner Medical Dictionary. TheFreeDictionary.com. August 12, 2014 reading. "A compound derived from a steroid in which there has been a ring cleavage."
4. ^ Hanson JR (2010). "Steroids: partial synthesis in medicinal chemistry". Nat Prod Rep 27 (6): 887–99. doi: 10.1039/c001262a. It is http://pubs.rsc.org/en/content/articlelanding/2010/np/c001262a#!divAbstract. PMID 20424788 

Outside link

• Secosteroids - the US National Library of Medicine Medical Subject Headings (MeSH)

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