2017년 1월 25일 수요일

Isoflavone 4'-O-methyl transferase

Isoflavone 4'-O-methyl transferase

Isoflavone 4'-O-methyl transferase
Identifier
EC number 2.1.1.46
CAS registration number 55,071-80-2
Database
IntEnz IntEnz view
BRENDA (English version) BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structure RCSB PDB PDBe PDBj PDBsum
Gene オントロジー AmiGO / EGO

Isoflavone 4'-O-methyl transferase (Isoflavone 4'-O-methyltransferase, EC 2.1.1.46) is an enzyme catalyzing the following chemical reactions.

S-adenosyl-L-methionine + isoflavoneS-adenosyl-L-homocysteine +4'-O-methyl isoflavone

Therefore, as for the substrate of two of this enzyme, S-adenosyl-L-methionine and 5,6,3',4'-tetrahydroxy-3,7-ジメトキシフラボイソフラボン, two products are S-adenosyl-L-homocysteine and 4'-O-methyl isoflavone.

This enzyme belongs to the family of the methyl transferase letting a transferase particularly 1 carbon group metastasize. The systematic name is S-adenosyl-L-methionine: It is isoflavone 4'-O-methyl transferase (S-adenosyl-L-methionine:isoflavone 4'-O-methyltransferase). This enzyme participates in isoflavonoid biosynthesis.

Source

  • Wengenmayer H, Ebel J, Grisebach H (1974). "Purification and properties of a S-adenosylmethionine: isoflavone 4'-O-methyltransferase from cell suspension cultures of Cicer arietinum L." Eur. J. Biochem. 50 (1): 135–43. doi: 10.1111/j.1432-1033.1974.tb03881.x. PMID 4452353. 

This article is taken from the Japanese Wikipedia Isoflavone 4'-O-methyl transferase

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