Glyoxylic acid

Glyoxylic acid
IUPAC name Oxoethanoic acid
Another name Formyl formic acid Oxoacetic acid
Identification information
CAS registration number	298-12-4
ChemSpider	740
SMILES O=CC(O)=O
Characteristic
Chemical formula	C2H2O3
Molar mass	74.04 g mol-1
Density	g cm-3
Melting point	-93 degrees Celsius
The boiling point	111 degrees Celsius
I can put a case, the data without the special mention for normal temperature (25 degrees Celsius), the ordinary pressure (100 kPa).

The glyoxylic acid (グリオキシル, glyoxylic acid) is a kind of carboxylic acid having aldehyde group and a carboxyl group in 1 molecule. Some plants and fungi last and they are combined with acetyl CoA and make malic acid with the glyoxylate cycle enabling gluconeogenesis from lipid. In addition, I am used as a reducing agent of the electroless plating.

When receive the oxidation with an intermediate in the body when the glyoxylic acid is metabolized to oxalic acid in the Homo sapiens by ethylene glycol, harmful oxalic acid will be generated [¹]; [²].

Pyridoxine (vitamin B6) has action to promote a switch to glycine by glycine transaminase that harmful oxalic acid does glyoxylic acid [³].

Footnote

1. Study, Shigeto Morokado, Yoshihide Ogawa about the oxalic acid precursor in the ^ experimental calcium oxalate calculus disease, Japanese urology department society magazine, Vol.86 (1995) No.5,JOI:JST.Journalarchive/jpnjurol1989/86.1022
2. ^ Carney, E.W. (1994) An integrated perspective on the developmental toxicity of ethylene glycol. Reprod. Toxicol. 8, 99-113
3. ^ renal tubule stroma-related nephritis: Tubulointerstitial disease Merck manual 18 Japanese edition

Allied item

• Ethylene glycol
• Glyoxal
• Glycolaldehyde
• Glycine dehydrogenase
• Glyoxylate cycle

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