NAD(P)+ nucleosidase
NAD(P)+ nucleosidase | |||||||||
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Identifier | |||||||||
EC number | 3.2.2.6 | ||||||||
CAS registration number | 9025-46-1 | ||||||||
Database | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA ( ) | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structure | RCSB PDB PDBe PDBj PDBsum | ||||||||
Gene オントロジー | AmiGO / EGO | ||||||||
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NAD(P)+ nucleosidase (NAD(P)+ nucleosidase, EC 3.2.2.6) is an enzyme catalyzing the following chemical reactions.
- NAD(P)+ + waterADP ribose (P) + nicotinamide
Therefore, this enzyme has NAD+ and two products of three substrates, ADP ribose and nicotinamide of NADP+ and the water.
These enzymes are classified in a hydrolase particularly glycosidase breaking down an N-glycosyl compound. The systematic name is NAD(P)+ glycohydrolase (NAD+ glycohydrolase). I may be called NAD(P) アーゼ, nicotinamide adenine dinucleotide (phosphoric acid) nucleosidase. I participate in metabolism of nicotinic acid and the nicotinamide.
Source
- ALIVISATOS SG, WOOLLEY DW (1956). "Solubilization and purification of the diphosphopyridine nucleotidase from beef spleen." J. Biol. Chem. 219 (2): 823–32. PMID 13319302.
- ZATMAN LJ, KAPLAN NO, COLOWICK SP (1953). "Inhibition of spleen diphosphopyridine nucleotidase by nicotinamide, an exchange reaction." J. Biol. Chem. 200 (1): 197–212. PMID 13034774.
- Zatman LJ, Kaplan NO, Colowick SP and Ciotti MM (1953). "Formation of the isonicotinic acid hydrazide analog of DPN." J. Am. Chem. Soc. 75 (13): 3293–3294. doi: 10.1021/ja01109a527.
This article is taken from the Japanese Wikipedia NAD(P)+ nucleosidase
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