2016년 11월 21일 월요일

D-malic acid dehydrogenase (decarboxylation)

D-malic acid dehydrogenase (decarboxylation)

D-malic acid dehydrogenase (decarboxylation)
Identifier
EC number 1.1.1.83
CAS registration number 37,250-20-7
Database
IntEnz IntEnz view
BRENDA (English version) BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structure RCSB PDB PDBe PDBj PDBsum
Gene オントロジー AmiGO / EGO

D-malic acid dehydrogenase (decarboxylation) (D-malate dehydrogenase (decarboxylating)) is an oxidation-reduction enzyme catalyzing the next chemical reaction.

(R)-Malate + NAD+ Pyruvate + CO2 + NADH

According to the equation, the substrate of this enzyme is (R) -Malic acid and NAD+, a product are pyruvic acid and carbon dioxide and NADH.

The organization name is (R) -In malate:NAD+ oxidoreductase (decarboxylating), it is D-malate dehydrogenase, D-malic enzyme, bifunctional L(+) for another name -tartrate dehydrogenase-D(+) -There is malate (decarboxylating).

It is one of the butyric acid metabolism enzymes.

References

  • Stern JR, O'Brien RW (1969). "Oxidation D-malic and beta-alkylmalic acids wild-type and mutant strains of Salmonella typhimurium and by Aerobacter aerogenes." J. Bacteriol. It is 147–51. 98 PMID 4889267. 

This article is taken from the Japanese Wikipedia D-malic acid dehydrogenase (decarboxylation)

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