Raji cell

Culture Raji cell.

The Raji cell (large さいぼう) strain is the first human-related cell strain to subculture consecutively derived from a hematopoietic (English version) cell [¹]. Based on a morphologic characteristic, the Raji cell is classified as lymphoblastic [²]. This floating cell comes from the B lymphocyte of the 11 years old male Nigerian Burkitt lymphoma patient in 1963. R. J. V. Pulvertaft established this cell strain for the first time [²]. The RPMI nutrient medium which serum was supplemented with is used for culture. I may not differentiate for the characteristic of the Raji cell, and the formation of the big aggregate consisting of several hundred cells is seen. The diameter of cell has a nucleus relatively greatly (5-8μm) uneven irregularly and wide cytoplasm with the free aggregate ribosome [³]. The Raji cell is unitary and grows up as fault kineticism, floating-related individual treatment or a doublet. Such as the pear which some cells are big, and is round with many nuclei extended it; have a shape [³].

The Raji cell is used widely to understand the malignant transformation of transfection host としてや, a hematopoietic cell or other cells. In addition, I am used for the detection of the immune complex (English version) because I develop many receptors for the complement ingredient in the same way as a Fc receptor for the immunoglobulin G [⁴].

Footnote

1. ^ B Fadeel (2005). "Raji revisited: cytogenetics of the original Burkitt' s lymphoma cell line". It is 159–161. doi: Leukemia 19 10.1038/sj.leu.2403534. http://www.nature.com/leu/journal/v19/n1/pdf/2403534a.pdf. 
2. ^ ^{a b} American Type Culture Collection Website. "ATCC-86: Raji Cell". February 3, 2012 reading.
3. ^ ^{a b} Cell Bank. "JCRB9012 [RAJI]". February 3, 2012 reading.
4. ^ Mondofacto, Medical Dictionary. "Raji cell". February 3, 2012 reading.

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