2016년 6월 11일 토요일

Glucose-1-dehydrogenase (NADP+)

Glucose-1-dehydrogenase (NADP+)

Glucose-1-dehydrogenase (NADP+)
Identifier
EC number 1.1.1.119
CAS registration number 37,250-50-3
Database
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structure RCSB PDB PDBe PDBj PDBsum
Gene オントロジー AmiGO / EGO

Glucose-1-dehydrogenase (NADP+) (glucose 1-dehydrogenase (NADP+), EC 1.1.1.119) is an enzyme catalyzing the following chemical reactions.

β-D-glucose + NADP+ This D-conspiracy-1,5-lactone + NADPH + H+

In other words, two substrate β-D-glucose, nicotinamide adenine dinucleotide phosphate (NADP) participate and lead it to this D-conspiracy-1,5-lactone, NADPH, H+ as three products.

The organization name of this enzyme is β-D-glucose: Nicotinamide adenine dinucleotide phosphate-binding アルドヘキソースデヒドロゲナーゼ (nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogenase) which is NADP+ 1 - oxide reductase (β-D-glucose:NAD(P)+ 1-oxidoreductase), NADP-binding アルドースデビトロゲナーゼ (NADP+-linked aldohexose dehydrogenase), glucose-1-dehydrogenase (NADP+) (is called glucose 1-dehydrogenase (NADP+) NADP+-dependent glucose dehydrogenase (NADP+-dependent glucose dehydrogenase).

And this enzyme belongs to an oxidation-reduction enzyme and I specifically act on a CH-OH group of the electronic donor and do NADP+ with an electronic receptor. This enzyme is found by bacteria (Acetobacter suboxydans), and NAD is not used unlike glucose-1-dehydrogenase (EC 1.1.1.47) seen in mammals. In addition, I act on D-mannose, 2-deoxy-D- glucose, 2-amino-2-deoxy- mannose [1].

Source

  1. ^ Ryuichi Yasugi and others (編), "glucose dehydrogenase," it is the fourth edition CD-ROM version, Iwanami Shoten, 1998 "Iwanami physics and chemistry dictionary".

Allied item

This article is taken from the Japanese Wikipedia Glucose-1-dehydrogenase (NADP+)

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