2016년 7월 13일 수요일

4-aminobenzoic acid-1-monooxygenase

4-aminobenzoic acid-1-monooxygenase

4-aminobenzoic acid-1-monooxygenase
Identifier
EC number 1.14.13.27
CAS registration number 98,668-55-4
Database
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structure RCSB PDB PDBe PDBj PDBsum
Gene オントロジー AmiGO / EGO

4-aminobenzoic acid-1-monooxygenase (4-aminobenzoate 1-monooxygenase) is an oxidation-reduction enzyme catalyzing the next chemical reaction.

4-aminobenzoic acid + NAD(P)H +2 H+ + O2 4-hydroxy aniline + NAD(P)+ + H2O + CO2

The substrate of this enzyme is a 4-aminobenzoic acid, NADH (or NADPH), H+ and O2, and the product is 4-hydroxy aniline, NAD+ (or NADP+), H2O and CO2. I use FAD as coenzyme.

As for the organization name, another name has 4-aminobenzoate hydroxylase, 4-aminobenzoate monooxygenase in 4-aminobenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating).

References

  • Tsuji H, Ogawa T, Bando N, Sasaoka K (1986). "Purification and properties of 4-aminobenzoate hydroxylase, a new monooxygenase from Agaricus bisporus." J. Biol. Chem. 261 (28): 13203–9. PMID 3489713. 

This article is taken from the Japanese Wikipedia 4-aminobenzoic acid-1-monooxygenase

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