2017년 6월 15일 목요일

Chaulmoogra oil

Chaulmoogra oil

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Chaulmoogra oil (だいふうしゆ) (English: Chaulmoogra oil, Hydnocarpus oil). The oils and fats which I made from the seed of the chaulmoogra (English: Chaulmoogra, Hydnocarpus wightiana) of the Idesia polycarpa department. It was spent for treatment of Hansen's disease for a long time, but was not used after the effectiveness for Hansen's disease of the sulfone agent system including glucosulfone sodium was discovered.

Table of contents

The history, an ingredient and effective

It is the fat oil which the chaulmoogra oil (だいふうしゆ) compresses it after removing the seed coat of the chaulmoogra (Hydnocarpus Anthelmintica) which is the seed of several kinds of plants belonging to the Idesia polycarpa department Hydnocarpus genus (move to dirt rear course with the APG plant classification system) and got. This does not have the smell that is strong in semisolid (semi-solid) at the normal temperature. I show the next material when I perform gas chromatography. It is the glycerin ester of mixtures such as an unsaturated cyclic fatty acid namely ヒドノカルピン sour (English: hydnocarpic acid) tea Ulu Moog phosphoric acid) (English: chaulmoogric acid), go Rick acid (English: gorlic acid) and a little palmitic acid.

I show an ointment-like property of the white in 搾油直後 and it is without taste or odor, but I gradually change in yellow and produce a special smell and branded taste. Originally it was a cure provided as Southeast Asia and an Indian folk remedy from the ancient times. It reaches China for the light の era, and, in 1578, prescription of the Chinese medicine is listed in a natural materials for medicinal use class and order as a therapeutic drug of Hansen's disease. I was used in Japan from the Edo era. I came to be used in Europe at the end of 19th century. I was rediscovered in the 1920s by Australian botanist Josef F rock and came to be generally used throughout the world.

I formulated ジノカルピン (Gynocarpin) fatty acid, and oral medicine, injection medicine was made from chaulmoogra oil in 1917 by British doctor, Sir Rodgers. HydroCulp Creek acid sodium preparation (oral medicine, injection medicine) was made afterwards in 1920. I was called "that pole" (English: alepol), and these were used led by India Burma which was a colony of the U.K. Various kinds of improvement was carried out afterwards. As injection medicine, I was published to produce the side effect of the digestive organ disorder by the internal use therapy in United States Pharmacopoeia.

The fault of the injection of the chaulmoogra oil might often leave suppuration and a nodule and a scar for the injection part. An effect was poor, and there were many opinions to be invalid, but the treatment by the chaulmoogra oil was performed in many countries because there being a report saying that it was effective if I compared it when I did not cure in chaulmoogra oil and a drug effective elsewhere did not exist. After the report that glucosulfone sodium of 1943 was effective, the treatment with chaulmoogra oil was not provided rapidly afterwards.

Study in Japan

Because it was written in the natural materials for medicinal use classes and order in Japan after the Edo era, I was used. L Vin phone ベルツ, Keizo Dohi, Ikuzo Tooyama, 中條資俊 accepted some effect. For 1,912 years, Kensuke Mitsuta aggravated 75% if I left nodule らいを, but wrote it for the documents when 88% did not produce a nodule if they injected it more than chaulmoogra oil 100cc. [1]In addition, he has the third international and others in Strasbourg in 1932 and announces that a relapse rate is high in a society. [2]Yutaka Kamikawa was given a degree for "remedial effective action for 癩 of the chaulmoogra oil in Kyoto University in 就 て" in 1930 [3]. When the chaulmoogra oil injection stimulates reticular Oriuchi cover cell line or a lymph system, and he occupies a local to systemic antibody-producing function if excellent, I do it. There is what I lead to the recovery from illness state in the terminal serious case example with impossibility though I assume it a conclusion and reduce a clinical treatment state in the early days of the affectation. [4]A house was an oil manufacturer, but, since 1892, it produced high quality chaulmoogra oil, and the Okamura flat soldier of the Imperial Guard of Sakai was famous as chaulmoogra oil of Okamura in Japan. [5]A huge pot melting by heat in chaulmoogra oil used for the national Hansen's disease museum in Tokyo before is displayed.

Documents

  • Tadayasu Tanimura, 櫻根太郎 "therapeutics chaulmoogra therapy 1954 Kinpara publication Co., Ltd. of 日本皮膚科全書癩臨床方面癩"
  • Value dermatology urology department magazine 1912 12 volumes 12 issue of the chaulmoogra oil for the Kensuke Mitsuta and others leprosy
  • Kazuo Saikawa "change 1999 Okinawa Hansen's disease preventive association of the Hansen's disease policy"
  • "All a benevolent act get out do it person Dr. Yutaka Kamikawa short biographies" (new life garden northeastern for 1,970 years)
  • Harumi Sakuma "治 らい agent "chaulmoogra oil" and 十九世瑞碩岡村平兵衛" 1986 Japan medical affairs Courier 3239 

Footnote

  1. ^ Mitsuta [1912: dermatology urology department magazine 12,12]
  2. ^ Saigawa [1,999:64]
  3. ^ doctoral dissertation bibliography database
  4. ^ Kamikawa [there is the thirteenth Japan 学会特別講演於仙台市]
  5. ^ 治 らい agent "chaulmoogra oil" and 十九世瑞碩岡村平兵衛 (1986) Harumi Sakuma, Japanese medical affairs Courier 3239

This article is taken from the Japanese Wikipedia Chaulmoogra oil

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