Phosphorylase
Generally phosphorylase (Phosphorylase) is the enzyme which performs phosphorylation (or phosphorolysis) of the compound as a substrate with a certain compound and inorganic phosphoric acid.
| Phosphorylase phosphorylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifier | |||||||||
| EC number | 2.4.1.1 | ||||||||
| CAS registration number | 9035-74-9 | ||||||||
| Database | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA () | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structure | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- A-B + H3PO4 → AOH + H2PO3-B
Because there is an equilibrium point near a midway point, these reactions are reversible. I often call an enzyme (glycogen phosphorylase) which breaks down glucan such as glycogen and starch or the Maruto dextrin into a narrow sense in particular, and produces glucose-1-phosphate (or conducts polymerization reaction adversely) phosphorylase.
Table of contents
Reaction
Phosphorylase as the general name is the enzyme which adds phosphoric acid derived from inorganic phosphoric acid to a receptor and is different from phosphatase (3.1.3 EC) and the kinase (phosphotransferase, EC 2.7) of the hydrolase. As for the phosphatase, the kinase uses the ATP for the removal of the phosphate group using water as a donor mainly.
| Enzyme name | Enzyme group | Reaction | Remarks |
|---|---|---|---|
| Phosphorylase | Transferase (EC 2.4 and EC 2.7.7) | A-B + H-OP A-OP + H-B | Metastasis basis = A = glycosyl or Nucleotidyl group |
| Phosphatase | Hydrolase (EC 3) | P-B + H-OH P-OH + H-B | |
| Kinase | Transferase (EC 2.7.1-2.7.4) | P-B + H-A P-A + H-B | Metastasis basis = P |
| P = phosphonic acid group, OP = phosphate group, H-OP and P-OH = no plane phosphoric acid | |||
Footnote
Allied item
Outside link
- Muscle phosphorylase deficiency - McArdle's Disease Website
- Phosphorylases - the US National Library of Medicine Medical Subject Headings (MeSH)
This article is taken from the Japanese Wikipedia Phosphorylase
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