2017년 6월 15일 목요일

ホスファチジルイノシトールデアシラーゼ

ホスファチジルイノシトールデアシラーゼ

ホスファチジルイノシトールデアシラーゼ (Phosphatidylinositol deacylase, EC 3.1.1.52) is an enzyme catalyzing the following chemical reactions.

ホスファチジルイノシトールデアシラーゼ
Identifier
EC number 3.1.1.52
CAS registration number 81,604-94-6
Database
IntEnz IntEnz view
BRENDA (English version) BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structure RCSB PDB PDBe PDBj PDBsum
Gene オントロジー AmiGO / EGO
1-ホスファチジル-D-myoinositol + water1-acyl glycero phosphoinositol + carboxylic acid

Therefore, as for the substrate, two, the product of 1-phosphatidylinositol and the water are two of 1-acyl glycero phosphoinositol and carboxylic acid.

These enzymes are classified in a hydrolase and act on ester bond in particular. The systematic name is 1-ホスファチジル-D-myoinositol 2 - acyl hydrolase (1-phosphatidyl-D-myo-inositol 2-acylhydrolase). I may be called phosphatidylinositol phospholipase A2 (phosphatidylinositol phospholipase A2) and phospholipase A2 (phospholipase A2).

Source

  • Gray NC, Strickland KP (1982). "The purification and characterization of a phospholipase A2 activity from the 106,000 X g pellet (microsomal fraction) of bovine brain acting on phosphatidylinositol." Can. J. Biochem. 60 (2): 108–17. PMID 7083039. 
  • Gray NC, Strickland KP (1982). "On the specificity of a phospholipase A2 purified from the 106,000 X g pellet of bovine brain." Lipids. 17 (2): 91–6. doi: 10.1007/BF02535181. PMID 7087686. 

This article is taken from the Japanese Wikipedia ホスファチジルイノシトールデアシラーゼ

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