3-hydroxy-2-methyl pyridinecarboxylic acid dioxygenase
3-hydroxy-2-methyl pyridinecarboxylic acid dioxygenase (3-hydroxy-2-methylpyridinecarboxylate dioxygenase) is an oxidation-reduction enzyme catalyzing the next chemical reaction in one of the vitamin B6 metabolism enzymes.
| 3-hydroxy-2-methyl pyridinecarboxylic acid dioxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifier | |||||||||
| EC number | 1.14.12.4 | ||||||||
| CAS registration number | 37,256-69-2 | ||||||||
| Database | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA () | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structure | RCSB PDB PDBe PDBsum | ||||||||
| Gene オントロジー | AmiGO / EGO | ||||||||
| |||||||||
- 3-hydroxy-2-methyl pyridine-5-carboxylic acid + NAD(P)H + H+ + O2 2-(acetamidomethylene) succinic acid + NAD(P)+
According to the equation, as for the substrate of this enzyme, 3-hydroxy-2-methyl pyridine-5-carboxylic acid and NADH (or NADPH) and H+ and O2, a product are 2-(acetamidomethylene) succinic acid and NAD+ (or NADP+). I use FAD as cofactor.
The organization name is 3-hydroxy-2-methylpyridine-5-carboxylate,NAD(P)H:oxygen oxidoreductase (decyclizing), and another name has methylhydroxypyridinecarboxylate oxidase, 2-methyl-3-hydroxypyridine 5-carboxylic acid dioxygenase, methylhydroxypyridine carboxylate dioxygenase, 3-hydroxy-3-methylpyridinecarboxylate dioxygenase [incorrect].
References
This article is taken from the Japanese Wikipedia 3-hydroxy-2-methyl pyridinecarboxylic acid dioxygenase
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