2017년 5월 21일 일요일

Noriko Fujii

Noriko Fujii

Noriko Fujii (Noriko Fujii, 1951 (1951) November 12 -) is a Japanese chemist. A specialty is biochemistry. Kyoto University nuclear reactor laboratory and Kyoto University graduate school science graduate course professor. Tokyo Medical and Dental College doctor of medicine. In June, 1998, I win the third "meeting prize for encouragement of the Japanese woman scientist". Tokyo birth.

Table of contents

Educational background

Work experience

Achievements

The first person of fundamental researches of the aging that assumed a D-amino acid an index.

The result that continued the original study based on the unique idea is accepted and clears the frontier in protein chemistry and gets a high evaluation globally.

In late years it was revealed that the D-amino acid of the isolation took various physiological roles, and the D-amino acid meeting for the study was established, too. In this field, Japan is in a leading position globally.

I that you should mention specially

  • I did not intend to become a researcher from a beginning. Because I liked chemistry in the high school, I thought to advance to the physical science vaguely.
  • I know that a woman researcher plays an active part from a newspaper article at a fermentation-related research institute and, before university entrance into a school of higher grade, am just interested in food chemistry. Therefore I entered the agricultural chemistry department of the department of agriculture.
  • I studied the glyco-protein of the skin in solution properties of matter, a doctoral course of the biopolymer with a master's course.
  • When I found work in a laboratory of Tsukuba University, the amino acid was comprised only of a left hand type (L-form) in the creatures in the one which there should be two kinds equally of a left hand type (L-form) and the right hand type (D form) and knew that it was dripped even in a process of the chemical evolution for the first time.
  • Then the aging was for reverse of the evolution and thought that the amino acid of the right hand type which was not L-form (D form) might be found if I checked an aging organization.
  • In the protein only for left hand types (L-form), it was thought that it was impossible that the amino acid of the right hand type (D form) was mixed in those days.
  • I announced the results of research that an amino acid gradually varies from L-form to D form in the calm temperature environment that is in the living body, but did not attract attention in contents far apart from the common sense at the time.
  • Result was finally recognized by having pinpointed the part of D-aspartic acid (D-Asp) in crystalline lens constitution protein of the Homo sapiens.
  • I discovered it about D-aspartic acid (D-Asp) being accumulated at the aging organization of the human body, the role of ultraviolet rays in the formation.
  • A researcher had few studies of the D-amino acid residue in protein in the 80s when Fujii has begun to wrestle, but it is now in the global research field.

Specialized field

  • The protein damage caused by the radiation
  • Biochemical study of the metallothionine using an activation analysis
  • It is racemized ultraviolet rays and the skin protein

Main article

  • "A D-amino acid and aging in protein" (reliable scientific academy)
  • "The role of the radiation in the origin, the evolution of the life" (Kyoto University, joint work)

References

Outside link

This article is taken from the Japanese Wikipedia Noriko Fujii

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