Yoshio Okada

Yoshio Okada (おかだよしお, from March 10, 1928 to January 16, 2008) is a cell biologist. Professor emeritus at Osaka University. A pioneer of the cellular engineering that discovered "the cell fusion phenomenon" that was a biotechnological basic technique. HiroshimaKure-shiA native place.　

Table of contents

Brief career history

• Hiroshima Prefectural Kure first junior high school graduation
• Kochi Senior High School graduation
• I am a graduate from - Naval Academy for 1,945 years (the 75th)
• March, 1952 - Osaka University medical department graduation
• July, 1953 - Res. Inst. for Microbial Diseases, Osaka Univ. assistant (prevention of epidemics department)
• April, 1962 - Res. Inst. for Microbial Diseases, Osaka Univ. assistant professor
• October, 1973 - Res. Inst. for Microbial Diseases, Osaka Univ. professor
• Mayor of April, 1982 - Osaka University cellular engineering center (until March, 1987)
• July, 1990 - Chisato life science promotion foundation chief director (until March, 2007) Foundation
• March, 1991 - Osaka University retirement age retirement　
• April, 1991 - Osaka University honorary professor [¹] [²]
• I die because of - dissociation-related aortic aneurysm on January 16, 2008, and 79 years old is rejected. 叙従三位.

Achievement

After injecting a virus into a cancer cell in 1955 after having become an assistant at Res. Inst. for Microbial Diseases, Osaka Univ., there was the huge cell which I had not looked at. It was a moment of the large discovery to overturn the biological common sense "that the cell of the creature was separated in a cell membrane each other, and the union might not have except the fertilization".

This virus which I used for technique to let a cell fuse by viral infection is known to the world as "Sendai virus" or HVJ (Japanese blood cohesion virus) for Tohoku University which is an origin of transportation to the United States.

The world's first article about the cell fusion that I announced in 1957 created a big sensation in Europe and America, and epoch-making great discovery and the best evaluation were given. Of combinations various after this including the cell fusion with a human being and the mouse understood that could fuse, and the genetics at the cell level and a study of the carcinogenesis due to the virus progressed drastically. In addition, as for the method to make the cell which the property of two kinds of cells was mixed in, it was in one of the biotechnological pillars with genetic modification. It is used in the development of a new medicine and the medical technology, the development of the new plant, the selective breeding of farm products, various fields including the improvement of the useful microbe. The influence that I gave to development of life sciences and the basic medicine is immeasurable. In late years it may be said that the artificial pluripotent trunk (iPS) cell of the professor at Shinya Yamanaka Kyoto University coming into the limelight as embryo stem cell is on this genealogy [³].
Okada became the pioneer who led to modern biotechnological development, but there were few people who understood the significance in the country at the time, and the study was connected for the development of flower difference life sciences in regular Europe and America of the environment.

Went ahead through a fusion reaction out of the cell, a somatic genetic study, the study of the somatic cellular engineering afterwards, and Okada contributed to bioscience, biotechnological development. I made an effort for the establishment of the cellular engineering center to become the base of the life sciences study in Osaka University and I acted as Manager first generation and brought up many excellent talented people. I was awkward, but I loved honest, warm personality, and there was no end to the researchers who came for consultation after retirement. In addition, I acted as the important posts such as Mayor of Japan Society for Cell Biology, the Ministry of Education Science Council committee.

Receiving a prize career, bestowal of an order career

• Asahi Prize (1971) (by the analysis of the cell fusion phenomenon) [⁴]
• Takeda medicine prize (1975) (by the discovery of the cell fusion phenomenon by the HVJ and application of the cellular engineering) [⁵]
• Japan Society of Human Genetics prize (1978)
• Fujiwara Prize (1979) (by discovery and the study of the cell fusion phenomenon by the HVJ) [⁶]
• The Imperial Award of the Japan Academy, Japanese Academy award (1980) (by the analysis of the cell fusion phenomenon and application of the cellular engineering) [⁷]
• Persons of cultural merits (1982)
• The Order of Culture (1987)
• The Grand Cordon of the Order of the Sacred Treasure (2000)
• HiroshimaHonorary citizen of the prefecture（1989）

Footnote

1. The Director of career during Osaka University holding the post from ^ graduation from university and life science foundation retirement year, the month is 49 pages on, Osaka University general affairs department evaluation, public relations section, February 20, 2008 in "news of death" "Osaka University NOW" NO.102 2008 February.
2. The Director of ^ life science foundation assumption of office year, the month is "LF talk" "Chisato life science promotion foundation news" NO.50, Chisato life science promotion foundation Foundation, page 5.
3. ^ Yomiuri Shimbun, March 6, 2008 28 pages
4. Prize winner of the ^ Asahi Prize past
5. ^ Takeda medicine prize prize winner
6. ^ Fujiwara Prize prize winner
7. ^ List of Lord of Imperial Award of the Japan Academy, Academy award, Japan Academy Edinburgh Prize awarding, Japan | The Japan Academy

Main book

• "Cell fusion" (1971)
• "A cell action and organogeny" (1973)
• "Cell fusion and cellular engineering" (1976)
• "Somatic cell genetics" joint work (1981)
• "The increase of cell" (1989)
• "Cell fusion and life sciences" (2001)

Outside link

• scientist: Yoshio Okada
• Chisato life science promotion foundation
• Hiroshima honor citizen of the prefecture - Yoshio Okada
• asahi.com: Pioneer of the cellular engineering, the Order of Culture receipt of a decoration Yoshio Okada death

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