Pyrrole nt phosphorus

Pyrrole nt phosphorus
IUPAC name 3-chloro-4-(3-chloro-2-nitrophenyl) -1H-pyrrole
Identification information
CAS registration number	1018-71-9
PubChem	13916
KEGG	D01094
SMILES C1=CC(=C(C(=C1)Cl)[N+](=O)[O-]) C2=CNC=C2Cl
Characteristic
Chemical formula	C10H6Cl2N2O2
Molar mass	257.07284
Melting point	124.5℃[1]
The risk
LD-50 LD50	> 2,000 mg·kg-1 (rat, oral) [1] 86 mg·kg-1 (mouse, the abdominal cavity) [1]
I can put a case, the data without the special mention for normal temperature (25 degrees Celsius), the ordinary pressure (100 kPa).

A kind of an antibiotic, the antifungus that pyrrole nt Lin (British: Pyrrolnitrin) has a pyrrole ring. I am combined with athlete's foot medicine.

Action mechanism

It is discovery, an isolated antibiotic from eubacteria Pseudomonas pyrrocinia of the black rot genus of the habitation out of the soil. I am effective in controlling breathing and metabolism for Trichophyton and マラセチア bacteria, and preventing growth and an increase. ^[2]I am given it as medicine for external application locally. It is often used in medical mixture with clotrimazole without a rest what is used alone.

Footnote

1. ^ ^{a b c} ChemIDplus
2. ^ Micutrin^®: Riassunto delle Caratteristiche del Prodotto (Zusammenfassung der Merkmale des Arzneimittels), Pharmacia Italia S.p.A. Stand März 2002.

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