Neurotransmitter
Neurotransmitter(Shin Tadasu Musetto,: Neurotransmitter) is a substance mediating information transmission in. Synaptic cells have a neurotransmitter synthesis system, and postsynaptic cells have neurotransmitters. Neurotransmitters are inactivated after release. Zinc ions affecting postsynaptic cells are neurotransmitters in the broad sense. Is also an intercellular mediator that binds to the receptor. The neurotransmitter acts locally, and the hormone acts globally through circulatory system and the like. It has the same effect.
table of contents
Mechanism
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- -
before release
Neurotransmitters are synthesized in pre-cells and are either carried by cell transport or absorbed from the outside and are stored at the end of the presynaptic process. Neurotransmitters are released to the presynaptic terminal when it reaches the end.
after release
When released into the neurotransmitter, it spreads by and is activated in association with receptors on postsynaptic cells. If the receptor is a type, it opens and if the receptor is a metabolic form, it will be opened through several steps afterwards, causing the postsynaptic cells to become absent. After release, it is inactivated promptly or reconstituted at the presynaptic terminal and part is again stored in synaptic vesicles and recycled (not to return to the original synaptic vesicle but to another synaptic vesicle It is filled in the cell).
Classification
Neurotransmitters can be broadly classified into the following three.
1. ((,,, etc.) 2. Types (,, etc.) 3. Class (,,) and
Others also show neurotransmitter-like actions.
Major neurotransmitters
Amino acids
-
- (Glu)
- (GABA)
- (Gly) *
Acetylcholine
- (ACh)
Monoamines
For details, see
Is synthesized from the following.
_, More synthesized (via synthetic route) _
- (DA)
- (NAd)
- (Ad)
-
-
- (PEA)
-
- (PEOH)
_ Synthesized from _
- (5-hydroxytryptamine, 5-HT)
- (Mel) (It is derived from serotonin but not monoamine)
_ Synthesized from _
- (H)
Polypeptides (neuropeptides)
As well.
-
- (GRP)
-
-
- (CGRP)
-
Gastrins
-
- (CCK)
Neurohypophyseal
Neuropeptide Y
- (NAAG) ()
- (NY)
- (PP)
- (PYY)
Secretins
-
-
-
- (VIP)
-
-
- (PACAP)
- (GRF)
Somatostatin
*
Kind
-
-
-
- Gamma neuropeptide *
-
-
Other
- (NO)
- (CO)
-
-
-
-
- (ATP)
-
-
-
-
(ADP)
*
footnote
1.
Related item
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External link
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- \ - Commentary on FM 1-43, a pigment that visualizes the release of synaptic granules.
This item is related to****. I will do (/). — | —
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Post Date : 2018-01-27 09:30
This article is taken from the Japanese Wikipedia Neurotransmitter
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