Chalcon

Chalcon - - | 1,3-Diphenyl-2-propen-1-one Alias ​​| Benzalacetophenone | C15 H12 O | 208.25 | [94-41-7] Shape | colorless solid And | 1.0712 g / cm 3, solid | 57-58 ° C | 345-348 ° C Source

Chalcone(chalcone) is one of the following. 1,3-diphenyl-2-propen-1-one.

It becomes a substrate of (Auwers synthesis).

Various derivatives having a structure of chalcone are known as biological substances, some of which have antibacterial, antibacterial, antitumor and anti-inflammatory properties. In the biosynthesis of chalcone derivatives, intermediates are also used. In a broad sense, these Chalconesare also sometimes called "chalcone".

Synthesis

Chalcone is synthesized with and, and at that time base such as catalyst is used.

This reaction is also possible as a solid phase synthesis without solvent, and it is considered as a subject of practical training at undergraduate undergraduates as an example of a synthetic method () with less burden on the environment. High temperature (200 - 350 ° C) There is also reported a method of reacting in an aqueous solution of no catalyst.

References

1. *Merck Index, 13th ed., 2045. 2. *Kohler, E. P .; Chadwell, H. M. Org. Synth. , Coll. Vol. 1, p. 78 (1941). 3. *Toda, F., Tanaka, K .; Hamai, K. J. Chem. Soc., Perkin Trans. 1 *1990, 3207. DOI: 4. *Palleros, D. R. J. Chem. Educ. *2004, _ 81 , 1345. 5. *Comisar, C. M .; Savage, P. E. Green Chem. *2004, _ 6 , 227 - 231 DOI:

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Post Date : 2018-01-25 04:00

This article is taken from the Japanese Wikipedia Chalcon

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