Fc receptor

Fc Receptor(Fc Juyuuu, Fc receptor, FcR) is a protein against the Fc site of (antibody) molecule and exists on the cell surface. Receptors for immunoglobulin molecules ,,, are called FcγR, FcαR, FcεR, FcμR, respectively.

function

Intracellular uptake of antigen via Fc receptor.

It is known that not only the role of Fc receptor as a simple device for antibody binding but also antibody binding is involved in cellular function regulation, and the influence thereof depends on the type of cell and receptor class It is different. Although most Fc receptors act to activate immunity, FcγRIIB is the only Fc receptor that conveys inhibitory activity. Fc receptors have functions such as phagocytosis of molecules captured by antibodies and enhancement of antigen presenting ability.

References

1. *Takai, T. (2002). "Roles of Fc receptors in autoimmunity." Nat. Rev. Immunol. *2: 580-592.

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Post Date : 2018-02-18 23:00

This article is taken from the Japanese Wikipedia Fc receptor

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